Cleveland Clinic Receives $7.9 Million Grant from NIH to Form Radiation Oncology-Biology Integration Network (ROBIN)
09/23/2022

Precision cancer medicine is the goal of a new multidisciplinary study, led by Dr. Tim Chan, examining radiation therapy combined with targeted therapy

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New Cleveland Clinic Centers of Excellence Target “Long COVID,” Myeloid Leukemia, Gut Microbiome
09/23/2022

The program, which has funded 21 research teams since 2015, has a proven record of supporting projects that go on to attract large external grants.

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HSD3B1 Research Shows Association Between Genotype and Endometrial Cancer
09/08/2022

Latest novel finding adds to list of cancers associated with the HSD3B1 gene; clinical and research teams investigating potential connections.

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New Research Sheds Light on “Evolutionary Games” between Cancer and Healthy Cells in Targeted Therapy-Resistant Lung Cancer
07/06/2022

Understanding cell growth dynamics may be the key to controlling therapeutic resistance.

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Researchers Find Potential for Repurposing Drug to Target Certain Types of Leukemia Cells
05/19/2022

Drs. Jha and Maciejewski have identified eltrombopag as a potent inhibitor of specific leukemia cells, which could lead to new drugs that target leukemia cells while preserving and expanding normal blood cells.

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Cancer Treatment Approach Developed by LRI Researchers Proven Feasible in Clinical Study
09/20/2021

Dr. Scott invented a new radiation planning technique called Temporally Feathered Radiation Therapy to reduce toxicity, which has now been shown to be safe and feasible in a small clinical study.

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Study Confirms Effectiveness of New Personalized Approach for Radiation Therapy
08/04/2021

Dr. Scott and colleagues validated the genomic-adjusted radiation dose to be beneficial as a pan-cancer predictor of radiation therapy efficacy in new clinical study.

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LRI Postdoc Selected for Esteemed Howard Hughes Medical Institute Fellowship
02/18/2021

Dr. Card, a postdoctoral fellow in the Scott lab, has been named a 2020 Hanna Gray Fellow, a fellowship that helps provide support for underrepresented and early-career biomedical researchers.

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Concurrent Chemotherapy and Antibiotic Use Associated with Epithelial Ovarian Cancer Outcomes
12/28/2020

Findings from a new retrospective study reveal that caution should be practiced when prescribing antibiotics to patients as antibiotic therapy is associated with decreased overall survival among women with the ovarian cancer.

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Combining Genomics and Mathematics Helps Personalize Radiation Therapy for Lung Cancer
12/14/2020

Rather than a one-size-fits-all approach, new technology from Dr. Scott provide opportunity to choose personalized radiation dose to improve outcomes and reduce toxicity.

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Cancer Researchers Identify Potential New Class of Drugs to Treat Blood and Bone Marrow Cancers
12/11/2020

Drs. Maciejewski and Jha developed a small molecule that selectively targeted and effectively eliminated cancer cells with a certain genetic mutation in preclinical models of myeloid leukemia, while simultaneously granting survival advantage to healthy cells.

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Adapting Ideas from Quantum Physics to Calculate Alternative Interventions for Infection and Cancer
08/24/2020

A team co-led by Dr. Scott shows for the first time how ideas from quantum physics can be translated and applied to biological problems, laying the foundation for a potential new area of study entirely, called quantum-inspired biological control.

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Department of Defense Awards $2.4M for Bladder Cancer Immunotherapy Research
03/24/2020

Drs. Mian, Gupta and Hwang—a multi-disciplinary team of researchers and clinicians—will look for ways to optimize immune checkpoint inhibitor therapy, including testing novel combinatory treatments and identifying predictive biomarkers of treatment response.

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Understanding the Balance Between Ecological and Evolutionary Contributors to Cancer
11/26/2019

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Using Artificial Intelligence to Deliver Personalized Radiation Therapy
06/26/2019

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Five Researchers Win Annual Fund Grants
01/09/2019

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When Cancer Cells Compete: Measuring Evolutionary 'Games' in Cancer
12/21/2018

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Research Team Identifies Mutation that Promotes Liver Cancer
08/31/2017

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