The Department of Inflammation & Immunity advances scientific understanding by bringing together a dedicated and collaborative team of scientists at the forefront of immunologic and organ-based research, to deliver impactful translational science that improves the health and well-being of patients at Cleveland Clinic and across the globe.

Working side-by-side with physicians to study patients and diseases, Inflammation & Immunity scientists address challenging questions to uncover the root causes of inflammatory diseases, and ultimately translate these discoveries into new diagnostic testing, therapies and preventive measures for patients. Learn more about us.

Department News


Dr. Thaddeus Stappenbeck Appointed to the Sherwick Endowed Chair in Inflammation and Immunity

The Sherwick Endowed Chair provides impactful research opportunities to improve understanding of the immune system and inflammatory diseases and develop better preventive and therapeutic responses

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NIH Grant to Advance the Study of Cholestatic Liver Diseases

Dr. Sakaguchi and his team will investigate the molecular mechanisms and malfunctions of the biliary system to develop new treatments for liver diseases.

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The STAR Consortium Awarded $5.3 Million from the Helmsley Charitable Trust to Develop Next Generation Biomarker Tools for Crohn’s Disease Patients

The STAR consortium, led by coordinating PI Dr. Rieder, seeks to identify and develop novel biomarkers to help establish effective therapeutics for Crohn’s disease patients with fibrosis.

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Exciting investigation and groundbreaking discovery happens every day at Cleveland Clinic. Join our team of expert researchers at the Department of Inflammation & Immunity.