Our Mission

The Cleveland Clinic Center for Therapeutics Discovery (C3TD) was recently established with the mission to promote the translation of basic science discoveries by Cleveland Clinic researchers into new therapeutics. Through collaboration with investigators we de-risk promising approaches and illuminate fundamental biology using small molecule chemical probes. We have established a pipeline of innovative research programs directed toward improving patient care with a true bench-to-bedside vision.

To achieve these goals, we use state of the art technologies in small molecule library screening, fragment-based methods, X-ray crystallography, computational tools, and target validation towards generating starting points for nascent hit-to-lead and lead optimization campaigns. These multi-disciplinary approaches complement the strong team culture and collaborative research at the Cleveland Clinic, and partnerships are developed with a keen focus on training and sharing best practices in the drug discovery process.

Join Us

The Cleveland Clinic Center for Therapeutics Discovery is a growing facility, and has immediate openings for talented and accomplished scientists. We are seeking candidates with a range of experience levels across multiple disciplines, notably medicinal chemistry; biochemistry, including small molecule screening; cell biology; and structural biology.

Please see our careers page for further details. If interested, please send a cover letter detailing your relevant experience, a curriculum vitae, and research summary to Dr. Shaun Stauffer.